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Cubs vs. Marlins Predictions, Betting Odds, Picks – Wednesday, September 21, 2022
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OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Chicago Cubs vs. the Miami Marlins on September 21, 2022 in Miami.
Opening Lines via DraftKings Sportsbook
As a note, all odds in this preview of Cubs vs. Marlins are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!
The Chicago Cubs visit the Miami Marlins for this MLB matchup on September 21, 2022. First pitch for Wednesday’s game is 6:40 p.m. ET / 3:40 p.m. PT in Miami.
The Miami Marlins are favored at -125 vs. the Chicago Cubs. The Chicago Cubs are +105 underdogs on the moneyline in this matchup and are +1.5 on the run line at -225.
The over/under for this matchup between the Cubs and the Marlins is set at 6.5, with the over 6.5 at -120 and the under 6.5 at +100.
Chicago Cubs vs. Miami Marlins Betting Odds, Over/Under, Run Lines:
| Team | Moneyline | Over/Under | Run Line |
|---|---|---|---|
| Chicago Cubs | +105 | O 6.5, -120 | +1.5 -225 |
| Miami Marlins | -125 | U 6.5, +100 | -1.5 +190 |
Looking to bet on this MLB matchup between the Chicago Cubs and the Miami Marlins?
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Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.
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FAQ
Who is the favorite in Chicago Cubs vs Miami Marlins?
The Miami Marlins are favored to win this MLB matchup, priced at -125 moneyline odds. The game will take place on September 21, 2022 in Miami.
What are the predictions for Chicago Cubs vs Miami Marlins game?
The Miami Marlins are predicted to win this MLB game. Upsets happen all the time in the MLB, but the Miami Marlins are favored by all online bookmakers. The Chicago Cubs are predicted to lose this game according to betting markets.
