Cardinals vs. Padres Predictions, Betting Odds, Picks – Wednesday, September 21, 2022

<p>St. Louis Cardinals&#8217; Albert Pujols (5) arrives for a spring training baseball game against the Washington Nationals, Wednesday, March 30, 2022, in West Palm Beach, Fla. (AP Photo/Sue Ogrocki)</p>

St. Louis Cardinals’ Albert Pujols (5) arrives for a spring training baseball game against the Washington Nationals, Wednesday, March 30, 2022, in West Palm Beach, Fla. (AP Photo/Sue Ogrocki)

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OddsJam StaffSeptember 21, 2022 at 01:46 AM

OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the St. Louis Cardinals vs. the San Diego Padres on September 21, 2022 in San Diego.

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TeamOdds
San Diego Padres Moneyline-110
St. Louis Cardinals Moneyline-110
San Diego Padres Run Line+1.5, -190
St. Louis Cardinals Run Line-1.5, +160
CardinalsPadres Over/Under7
Date & TimeSeptember 21, 2022 at 9:40 p.m. ET / 6:40 p.m. PT

Opening Lines via DraftKings Sportsbook

As a note, all odds in this preview of Cardinals vs. Padres are from opening lines. Odds can move at any time. Please check the table below for real-time betting odds!

The St. Louis Cardinals visit the San Diego Padres for this MLB matchup on September 21, 2022. First pitch for Wednesday’s game is 9:40 p.m. ET / 6:40 p.m. PT in San Diego.

Moneyline

The San Diego Padres are favored at -110 vs. the St. Louis Cardinals. The St. Louis Cardinals are -110 underdogs on the moneyline in this matchup and are -1.5 on the run line at +160.

The over/under for this matchup between the Cardinals and the Padres is set at 7, with the over 7 at -125 and the under 7 at +105.

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St. Louis Cardinals vs. San Diego Padres Betting Odds, Over/Under, Run Lines:

TeamMoneylineOver/UnderRun Line
St. Louis Cardinals-110O 7, -125-1.5 +160
San Diego Padres-110U 7, +105+1.5 -190
Odds via DraftKing Sportsbook

Looking to bet on this MLB matchup between the St. Louis Cardinals and the San Diego Padres

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FAQ

  1. Who is the favorite in St. Louis Cardinals vs San Diego Padres?

    The San Diego Padres are favored to win this MLB matchup, priced at -110 moneyline odds. The game will take place on September 21, 2022 in San Diego.

  2. What are the predictions for St. Louis Cardinals vs San Diego Padres game?

    The San Diego Padres are predicted to win this MLB game. Upsets happen all the time in the MLB, but the San Diego Padres are favored by all online bookmakers. The St. Louis Cardinals are predicted to lose this game according to betting markets.

  3. Where can I bet on this game?

    You can bet on this game on a variety of sportsbooks, including Caesars, BetMGM and FanDuel. The more books you sign up for, the better odds you can find!

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