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Astros vs. Orioles Predictions, Betting Odds, Picks – Friday, September 23, 2022
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OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Houston Astros vs. the Baltimore Orioles on September 23, 2022 in Baltimore.
Opening Lines via DraftKings Sportsbook
As a note, all odds in this preview of Astros vs. Orioles are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!
The Houston Astros visit the Baltimore Orioles for this MLB matchup on September 23, 2022. First pitch for Friday’s game is 7:05 p.m. ET / 4:05 p.m. PT in Baltimore.
The Houston Astros are favored at -145 vs. the Baltimore Orioles. The Baltimore Orioles are +125 underdogs on the moneyline in this matchup and are +1.5 on the run line at -135.
The over/under for this matchup between the Astros and the Orioles is set at 7.5, with the over 7.5 at -110 and the under 7.5 at -110.
Houston Astros vs. Baltimore Orioles Betting Odds, Over/Under, Run Lines:
| Team | Moneyline | Over/Under | Run Line |
|---|---|---|---|
| Houston Astros | -145 | O 7.5, -110 | -1.5 +115 |
| Baltimore Orioles | +125 | U 7.5, -110 | +1.5 -135 |
Looking to bet on this MLB matchup between the Houston Astros and the Baltimore Orioles?
Use OddsJam’s MLB Odds comparison tool to find the best odds on mainline markets like moneyline, run line and total, as well as every single MLB player prop at all major sportsbooks available in your state!
Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.
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FAQ
Who is the favorite in Houston Astros vs Baltimore Orioles?
The Houston Astros are favored to win this MLB matchup, priced at -145 moneyline odds. The game will take place on September 23, 2022 in Baltimore.
What are the predictions for Houston Astros vs Baltimore Orioles game?
The Houston Astros are predicted to win this MLB game. Upsets happen all the time in the MLB, but the Houston Astros are favored by all online bookmakers. The Baltimore Orioles are predicted to lose this game according to betting markets.
