Subscribe to our newsletter
We'll send you bets and resources to help you profit
Los Angeles Rams vs. San Francisco 49ers Predictions, Betting Odds & Picks – Week 4 Monday, October 3, 2022
AP Photos
OddsJam’s NFL experts take you through the betting odds, picks and predictions for this matchup between the Los Angeles Rams and the San Francisco 49ers.
This game is set to kick off on October 3, 2022. The San Francisco 49ers are at home for this game.
Check out the Positive EV Betting Tool on OddsJam to find the sharpest, data-driven bets!
Los Angeles Rams vs. San Francisco 49ers Betting Odds
The Los Angeles Rams visit the San Francisco 49ers for this NFL match up on October 3, 2022. Kickoff for Monday’s game is 8:15 p.m. ET / 5:15 p.m. PT.
As a note, all odds in this NFL preview of San Francisco 49ers vs. Los Angeles Rams are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!
The San Francisco 49ers are favored at -135 moneyline odds at Caesars. The Los Angeles Rams are +115 underdogs on the moneyline in this matchup vs. the San Francisco 49ers and +2 on the point spread at -110 odds.
The over/under for this matchup between the Los Angeles Rams and the San Francisco 49ers is set at 42.5, with the over 42.5 at -105 and the under 42.5 at -115 odds.
Subscribe to OddsJam to get access to all of our sharp sports betting tools.
Los Angeles Rams vs. San Francisco 49ers Betting Odds, Over/Under, Point Spreads:
| Team | Moneyline | Over/Under | Point Spread |
|---|---|---|---|
| Los Angeles Rams | +115 | O 42.5, -105 | +2 -110 |
| San Francisco 49ers | -135 | U 42.5, -115 | -2 -110 |
Looking to bet on this NFL matchup between the Los Angeles Rams and the San Francisco 49ers?
Use OddsJam’s sports betting tools to find the best bets on mainline markets like moneyline, point spread and total, as well as every single NFL player prop at all major online sportsbooks available in your location! We recommend Caesars, BetMGM, FanDuel and DraftKings.
Want to learn more on how to bet on NFL football? You can find out much more in our Betting Education hub. We also recommend learning about line shopping and Positive EV betting.
