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Rays vs. Guardians Predictions, Betting Odds, Picks – Wednesday, September 28, 2022

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OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Tampa Bay Rays vs. the Cleveland Guardians on September 28, 2022 in Cleveland.

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Team	Odds
Cleveland Guardians Moneyline	-130
Tampa Bay Rays Moneyline	+110
Cleveland Guardians Run Line	-1.5, +175
Tampa Bay Rays Run Line	+1.5, -205
RaysGuardians Over/Under	6.5
Date & Time	September 28, 2022 at 6:10 p.m. ET / 3:10 p.m. PT

Opening Lines via DraftKings Sportsbook

As a note, all odds in this preview of Rays vs. Guardians are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!

The Tampa Bay Rays visit the Cleveland Guardians for this MLB matchup on September 28, 2022. First pitch for Wednesday’s game is 6:10 p.m. ET / 3:10 p.m. PT in Cleveland.

The Cleveland Guardians are favored at -130 vs. the Tampa Bay Rays. The Tampa Bay Rays are +110 underdogs on the moneyline in this matchup and are +1.5 on the run line at -205.

The over/under for this matchup between the Rays and the Guardians is set at 6.5, with the over 6.5 at -125 and the under 6.5 at +105.

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Tampa Bay Rays vs. Cleveland Guardians Betting Odds, Over/Under, Run Lines:

Team	Moneyline	Over/Under	Run Line
Tampa Bay Rays	+110	O 6.5, -125	+1.5 -205
Cleveland Guardians	-130	U 6.5, +105	-1.5 +175

Odds via DraftKing Sportsbook

Looking to bet on this MLB matchup between the Tampa Bay Rays and the Cleveland Guardians?

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FAQ

Who is the favorite in Tampa Bay Rays vs Cleveland Guardians?
The Cleveland Guardians are favored to win this MLB matchup, priced at -130 moneyline odds. The game will take place on September 28, 2022 in Cleveland.
What are the predictions for Tampa Bay Rays vs Cleveland Guardians game?
The Cleveland Guardians are predicted to win this MLB game. Upsets happen all the time in the MLB, but the Cleveland Guardians are favored by all online bookmakers. The Tampa Bay Rays are predicted to lose this game according to betting markets.
Where can I bet on this game?
You can bet on this game on a variety of sportsbooks, including Caesars, BetMGM and FanDuel. The more books you sign up for, the better odds you can find!