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Astros vs. Rays Predictions, Betting Odds, Picks – Wednesday, September 21, 2022
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OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Houston Astros vs. the Tampa Bay Rays on September 21, 2022 in Tampa Bay.
Opening Lines via DraftKings Sportsbook
As a note, all odds in this preview of Astros vs. Rays are from opening lines. Odds can move at any time. Please check the table below for real-time betting odds!
The Houston Astros visit the Tampa Bay Rays for this MLB matchup on September 21, 2022. First pitch for Wednesday’s game is 6:40 p.m. ET / 3:40 p.m. PT in Tampa Bay.
The Houston Astros are favored at -130 vs. the Tampa Bay Rays. The Tampa Bay Rays are +110 underdogs on the moneyline in this matchup and are +1.5 on the run line at -155.
The over/under for this matchup between the Astros and the Rays is set at 7, with the over 7 at +105 and the under 7 at -125.
Houston Astros vs. Tampa Bay Rays Betting Odds, Over/Under, Run Lines:
| Team | Moneyline | Over/Under | Run Line |
|---|---|---|---|
| Houston Astros | -130 | O 7, +105 | -1.5 +135 |
| Tampa Bay Rays | +110 | U 7, -125 | +1.5 -155 |
Looking to bet on this MLB matchup between the Houston Astros and the Tampa Bay Rays?
Use OddsJam’s MLB Odds comparison tool to find the best odds on mainline markets like moneyline, run line and total, as well as every single MLB player prop at all major sportsbooks available in your state!
Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.
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FAQ
Who is the favorite in Houston Astros vs Tampa Bay Rays?
The Houston Astros are favored to win this MLB matchup, priced at -130 moneyline odds. The game will take place on September 21, 2022 in Tampa Bay.
What are the predictions for Houston Astros vs Tampa Bay Rays game?
The Houston Astros are predicted to win this MLB game. Upsets happen all the time in the MLB, but the Houston Astros are favored by all online bookmakers. The Tampa Bay Rays are predicted to lose this game according to betting markets.
