Astros vs. Cardinals Predictions, Betting Odds, Picks – 1:05 p.m. ET Thursday

OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Houston Astros vs. the St. Louis Cardinals.

Astros vs. Cardinals Betting Odds:

The Houston Astros visit the St. Louis Cardinals for this MLB matchup on March 21, 2024. First pitch for Thursday’s game is 1:05 p.m. ET / 10:05 a.m. PT in St. Louis.

Astros vs. Cardinals Prediction:

The Houston Astros are predicted to win with a 54.55% implied probability, according to betting markets, for this March 21, 2024 game.

Betting markets are also giving their opponent, the St. Louis Cardinals, a 50.0% implied probability to win this game.

Houston Astros vs. St. Louis Cardinals Moneyline

• The Houston Astros are favored at -120 odds vs. the St. Louis Cardinals. 
• The St. Louis Cardinals are a +100 moneyline underdog in this matchup and are +1.5 on the run line at -160 odds.

Make sure to line shop and ensure you are getting the best odds in your location. All locations have different sportsbooks! 

Although the Houston Astros are offered at -120 moneyline odds at Caesars, other online bookmakers in your location may have a better price. Shop for the best MLB lines here.

All odds in this MLB preview of Houston Astros vs. St. Louis Cardinals are from the opening lines. Odds can move at any time.

Houston Astros vs. St. Louis Cardinals Over/Under, Total

• The over/under for this matchup between the Houston Astros and the St. Louis Cardinals is set at 9.5, with the over 9.5 at -115 and the under 9.5 at -105 odds.

Houston Astros vs. St. Louis Cardinals Betting Odds, Over/Under, Run Lines:

Looking to bet on this MLB matchup between the Houston Astros and the St. Louis Cardinals? 

Use OddsJam’s MLB Odds comparison tool to find the best odds on mainline markets like moneyline, run line and total, as well as every single MLB player prop at all major sportsbooks available in your state!

Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.

FAQ

1. Who is the favorite in Houston Astros vs St. Louis Cardinals?
   The Houston Astros are favored to win this MLB matchup, priced at -120 moneyline odds. The game will take place on March 21, 2024 in St. Louis.
2. What are the predictions for Houston Astros vs St. Louis Cardinals game?
   The Houston Astros are predicted to win this MLB game. Upsets happen all the time in the MLB, but the Houston Astros are favored by all online bookmakers. The St. Louis Cardinals are predicted to lose this game according to betting markets.
3. Where can I bet on this game?
   You can bet on this game on a variety of sportsbooks, including Caesars, BetMGM and FanDuel. The more books you sign up for, the better odds you can find!