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MLB

Pirates vs. Yankees Predictions, Betting Odds, Picks – Wednesday, September 21, 2022

 

OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Pittsburgh Pirates vs. the New York Yankees on September 21, 2022 in New York.

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TeamOdds
New York Yankees Moneyline-300
Pittsburgh Pirates Moneyline+250
New York Yankees Run Line-1.5, -140
Pittsburgh Pirates Run Line+1.5, +120
PiratesYankees Over/Under8
Date & TimeSeptember 21, 2022 at 7:05 p.m. ET / 4:05 p.m. PT

Opening Lines via DraftKings Sportsbook

As a note, all odds in this preview of Pirates vs. Yankees are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!

The Pittsburgh Pirates visit the New York Yankees for this MLB matchup on September 21, 2022. First pitch for Wednesday’s game is 7:05 p.m. ET / 4:05 p.m. PT in New York.

The New York Yankees are favored at -300 vs. the Pittsburgh Pirates. The Pittsburgh Pirates are +250 underdogs on the moneyline in this matchup and are +1.5 on the run line at +120.

The over/under for this matchup between the Pirates and the Yankees is set at 8, with the over 8 at -115 and the under 8 at -105.

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Pittsburgh Pirates vs. New York Yankees Betting Odds, Over/Under, Run Lines:

TeamMoneylineOver/UnderRun Line
Pittsburgh Pirates+250O 8, -115+1.5 +120
New York Yankees-300U 8, -105-1.5 -140
Odds via DraftKing Sportsbook

Looking to bet on this MLB matchup between the Pittsburgh Pirates and the New York Yankees

Use OddsJam’s MLB Odds comparison tool to find the best odds on mainline markets like moneyline, run line and total, as well as every single MLB player prop at all major sportsbooks available in your state!

Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.


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FAQ

  1. Who is the favorite in Pittsburgh Pirates vs New York Yankees?

    The New York Yankees are favored to win this MLB matchup, priced at -300 moneyline odds. The game will take place on September 21, 2022 in New York.

  2. What are the predictions for Pittsburgh Pirates vs New York Yankees game?

    The New York Yankees are predicted to win this MLB game. Upsets happen all the time in the MLB, but the New York Yankees are favored by all online bookmakers. The Pittsburgh Pirates are predicted to lose this game according to betting markets.

  3. Where can I bet on this game?

    You can bet on this game on a variety of sportsbooks, including Caesars, BetMGM and FanDuel. The more books you sign up for, the better odds you can find!

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