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San Francisco 49ers vs. Denver Broncos Betting Odds, Picks and Predictions – Sunday, September 25, 2022
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OddsJam’s NFL experts take you through the betting odds, picks and predictions for this matchup between the San Francisco 49ers and the Denver Broncos. This game is set to kick off on September 25, 2022. The Denver Broncos are at home for this game.
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San Francisco 49ers vs. Denver Broncos Betting Odds
| Team | Odds |
|---|---|
| Denver Broncos Moneyline | -155 |
| San Francisco 49ers Moneyline | +130 |
| Denver Broncos Point Spread | -3, +100 |
| San Francisco 49ers Point Spread | +3, -120 |
| San Francisco 49ers–Denver Broncos Over/Under | 46 |
| Date & Time | September 25, 2022 at 8:20 p.m. ET / 5:20 p.m. PT |
The San Francisco 49ers visit the Denver Broncos for this NFL matchup on September 25, 2022. Kickoff for Sunday’s game is 8:20 p.m. ET / 5:20 p.m. PT.
The Denver Broncos are favored at -155 moneyline odds at Caesars. The San Francisco 49ers are +130 underdogs on the moneyline in this matchup vs. the Denver Broncos and +3 on the point spread at -120 odds.
The over/under for this matchup between the San Francisco 49ers and the Denver Broncos is set at 46, with the over 46 at -110 and the under 46 at -110 odds.
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San Francisco 49ers vs. Denver Broncos Betting Odds, Over/Under, Point Spreads:
| Team | Moneyline | Over/Under | Point Spread |
|---|---|---|---|
| San Francisco 49ers | +130 | O 46, -110 | +3 -120 |
| Denver Broncos | -155 | U 46, -110 | -3 +100 |
Looking to bet on this NFL matchup between the San Francisco 49ers and the Denver Broncos?
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