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San Francisco 49ers vs. Chicago Bears Betting Odds, Picks and Predictions – Sunday, September 11, 2022

<p>AP Photos</p>

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OddsJam’s NFL experts take you through the betting odds, picks and predictions for this matchup between the San Francisco 49ers and the Chicago Bears. This game is set to kick off on September 11, 2022. The Chicago Bears are at home for this game.

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San Francisco 49ers vs. Chicago Bears Betting Odds

TeamOdds
San Francisco 49ers Moneyline-310
Chicago Bears Moneyline+250
San Francisco 49ers Point Spread-6.5, -120
Chicago Bears Point Spread+6.5, -102
San Francisco 49ersChicago Bears Over/Under41.5
Date & TimeSeptember 11, 2022 at 1:00 p.m. ET / 10:00 a.m. PT
Odds via FanDuel Sportsbook

The San Francisco 49ers visit the Chicago Bears for this NFL matchup on September 11, 2022. Kickoff for Sunday’s game is 1:00 p.m. ET / 10:00 a.m. PT.

The San Francisco 49ers are favored at -310 moneyline odds on FanDuel. The Chicago Bears are +250 underdogs on the moneyline in this matchup vs. the San Francisco 49ers and +6.5 on the point spread at -102 odds.

The over/under for this matchup between the San Francisco 49ers and the Chicago Bears is set at 41.5, with the over 41.5 at -110 and the under 41.5 at -110 odds.

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San Francisco 49ers vs. Chicago Bears Betting Odds, Over/Under, Point Spreads:

TeamMoneylineOver/UnderPoint Spread
San Francisco 49ers-310O 41.5, -110-6.5 -120
Chicago Bears+250U 41.5, -110+6.5 -102
Odds via FanDuel Sportsbook

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49ers vs. Bears Pick: 49ers -6.5 | -120 at FanDuel

I get it, this is a large spread for a 49ers team that is starting a new quarterback in Trey Lance. As detailed in the 49ers season preview, Lance is historically raw as a QB prospect.

He has all the talent in the world but significantly lacks experience. With that said, why I’m rolling with the 49ers is because of the other side of the ball. The 49ers finished with the seventh-best defense in the NFL, according to DVOA, and if they can stay healthy I project them to be a top-five defense in 2022.

The Bears, meanwhile, have the second-worst offensive line according to PFF, and the literal worst group of pass catchers. I wouldn’t be surprised if the Bears didn’t even get to double digits in this one.

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