Kansas City Chiefs vs. Indianapolis Colts Betting Odds, Picks and Predictions – Sunday, September 25, 2022

<p>AP Photos</p>

AP Photos

OddsJam’s NFL experts take you through the betting odds, picks and predictions for this matchup between the Kansas City Chiefs and the Indianapolis Colts. This game is set to kick off on September 25, 2022. The Indianapolis Colts are at home for this game.

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Kansas City Chiefs vs. Indianapolis Colts Betting Odds

TeamOdds
Kansas City Chiefs Moneyline-165
Indianapolis Colts Moneyline+140
Kansas City Chiefs Point Spread-3, -115
Indianapolis Colts Point Spread+3, -105
Kansas City ChiefsIndianapolis Colts Over/Under52.5
Date & TimeSeptember 25, 2022 at 1:00 p.m. ET / 10:00 a.m. PT
Odds via Caesars Sportsbook

The Kansas City Chiefs visit the Indianapolis Colts for this NFL matchup on September 25, 2022. Kickoff for Sunday’s game is 1:00 p.m. ET / 10:00 a.m. PT.

Moneyline

The Kansas City Chiefs are favored at -165 moneyline odds at Caesars. The Indianapolis Colts are +140 underdogs on the moneyline in this matchup vs. the Kansas City Chiefs and +3 on the point spread at -105 odds.

The over/under for this matchup between the Kansas City Chiefs and the Indianapolis Colts is set at 52.5, with the over 52.5 at -110 and the under 52.5 at -110 odds.

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Kansas City Chiefs vs. Indianapolis Colts Betting Odds, Over/Under, Point Spreads:

TeamMoneylineOver/UnderPoint Spread
Kansas City Chiefs-165O 52.5, -110-3 -115
Indianapolis Colts+140U 52.5, -110+3 -105
Odds via Caesars Sportsbook

Looking to bet on this NFL matchup between the Kansas City Chiefs and the Indianapolis Colts

Use OddsJam’s sports betting tools to find the best bets on mainline markets like moneyline, point spread and total, as well as every single NFL player prop at all major online sportsbooks available in your location! We recommend CaesarsBetMGMFanDuel and DraftKings.

Want to learn more on how to bet on NFL football? You can find out much more in our Betting Education hub. We also recommend learning about line shopping and Positive EV betting.

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