Subscribe to our newsletter

The best bets and resources to make you more profitable

MLB

Giants vs. Rockies Predictions, Betting Odds, Picks – Wednesday, September 21, 2022

<p>AP Photos</p>

AP Photos

 

OddsJam’s MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the San Francisco Giants vs. the Colorado Rockies on September 21, 2022 in Colorado.

The OddsJam Positive EV Betting Tool is the only offering with a live data feed that identifies mathematically profitable betting opportunities in real time.

TeamOdds
San Francisco Giants Moneyline-135
Colorado Rockies Moneyline+115
San Francisco Giants Run Line-1.5, +115
Colorado Rockies Run Line+1.5, -135
GiantsRockies Over/Under10
Date & TimeSeptember 21, 2022 at 8:40 p.m. ET / 5:40 p.m. PT

Opening Lines via DraftKings Sportsbook

As a note, all odds in this preview of Giants vs. Rockies are from the opening lines. Odds can move at any time. Please check the table below for real-time betting odds!

The San Francisco Giants visit the Colorado Rockies for this MLB matchup on September 21, 2022. First pitch for Wednesday’s game is 8:40 p.m. ET / 5:40 p.m. PT in Colorado.

The San Francisco Giants are favored at -135 vs. the Colorado Rockies. The Colorado Rockies are +115 underdogs on the moneyline in this matchup and are +1.5 on the run line at -135.

The over/under for this matchup between the Giants and the Rockies is set at 10, with the over 10 at -105 and the under 10 at -115.

Download OddsJam’s player prop betting app today to find the player props with the best value across every MLB game and market.

San Francisco Giants vs. Colorado Rockies Betting Odds, Over/Under, Run Lines:

TeamMoneylineOver/UnderRun Line
San Francisco Giants-135O 10, -105-1.5 +115
Colorado Rockies+115U 10, -115+1.5 -135
Odds via DraftKing Sportsbook

Looking to bet on this MLB matchup between the San Francisco Giants and the Colorado Rockies

Use OddsJam’s MLB Odds comparison tool to find the best odds on mainline markets like moneyline, run line and total, as well as every single MLB player prop at all major sportsbooks available in your state!

Want to learn more on how to bet on the MLB? You can find our MLB Betting Guide, our MLB Prop Betting Guide and much more in our Betting Education hub.


Subscribe to our newsletter

The best bets and resources to make you more profitable


BONUS BETS

Worth $2,500

BetMGM logo

Bet $5, Get $150 in Bonus Bets - Guaranteed! Must be 21+. Gambling Problem? Call 1-800-GAMBLER.

Fanatics logo

Get up to $1,000 Bonus Bets!

bet365 logo

$1,000 First Bet Safety Net!

DraftKings logo

Bet $5, Get $150 Bonus Bets Instantly!

FanDuel logo

Bet $5, Get $200 in Bonus Bets If Your Bet Wins!

FAQ

  1. Who is the favorite in San Francisco Giants vs Colorado Rockies?

    The San Francisco Giants are favored to win this MLB matchup, priced at -135 moneyline odds. The game will take place on September 21, 2022 in Colorado.

  2. What are the predictions for San Francisco Giants vs Colorado Rockies game?

    The San Francisco Giants are predicted to win this MLB game. Upsets happen all the time in the MLB, but the San Francisco Giants are favored by all online bookmakers. The Colorado Rockies are predicted to lose this game according to betting markets.

  3. Where can I bet on this game?

    You can bet on this game on a variety of sportsbooks, including Caesars, BetMGM and FanDuel. The more books you sign up for, the better odds you can find!

Bonus Bets in Virginia

BetMGM

BetMGM

Fanatics

Fanatics

bet365

bet365

DraftKings

DraftKings

FanDuel

FanDuel